DMA® TecHnology

The revolutionary zero-invasive AI-native screening technology for early diagnosis and personalized medicine

DMA® (Deep Metabolic-process Assessment) is a non-invasive metabolic screening technology, developed by Math Biology, that enables the assessment of the body’s deep metabolic processes through the analysis of bioelectrical signals. Assessments are delivered through dedicated Human Biology Institutes (HBIs), specialized centers focused on health, prevention and performance.

Validated by data

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one visit, real answers.

100%
Non-Invasive

No needles, no radiation, just safe, repeatable, patient‑friendly diagnostics.

Detects Early, Before Symptoms

Identifies silent metabolic imbalances before disease manifests.

Truly Personalized Healthcare

Insights tailored to the individual’s biology, not statistical averages.

One Visit, 
Full Insight

Comprehensive, systemic picture in a single session.

Fast and 
Efficient

From 15 to 60 minutes, that’s all it takes.

Reduce Healthcare Costs

Cuts waste by guiding smarter diagnostics and more effective therapies.

Complements Existing Diagnostics

Enhances, not replaces, imaging and lab results.

Proprietary AI Algorithms

Processed via our cloud engine for real-time clinical insights.

Portable & Offline-Ready

Works without internet, even in remote or crisis environments.

A Game Changer for Global Access

Scalable, affordable, and accessible to underserved populations.

From Reaction 
To Prevention

DMA® device is able to identify altered biochemical reactions at the metabolic level within the human body, which are always linked to symptoms and diseases

By analyzing these patterns, we gain valuable insights into early health indicators, enabling proactive care before diseases manifest or worsen.

By combining AI and advanced mathematical models, we developed a wide set of protocols and software, permitting us to correlate subsets of such measures to the status of specific organs the Central Nervous System (CNS) or glands.

Why studying metabolism is a game-changer

Metabolism is a complex network of chemical reactions that keeps our body functioning, enabling us to think, move and breathe. It adapts to various activities like eating, sleeping, and exercising to meet our body’s needs.

However, metabolism also responds to health challenges, shifting when organs are under stress or when inflammation occurs. These changes are often undetectable at first, as they happen at the cellular and biochemical levels without causing noticeable symptoms.

That’s where our DMA® technology comes in. It can detect these subtle changes by measuring electrical currents, capturing data at the nanoampere level.

By analyzing metabolism, we can uncover these hidden shifts, allowing for early diagnosis and intervention before conditions worsen.

Smarter Prevention.
Stronger Performance.

DMA® screening

DMA® Screening equips trained healthcare professionals with a non-invasive tool to screen metabolic markers as part of their clinical workflow, supporting earlier, more informed conversations with patients.*

*DMA® Screening’s EU MDR Class I conformity process is at an advanced stage. Until this regulatory process is formally completed, the product must not be presented or implied as already CE-marked as a medical device.

DMA® performance

DMA® Performance gives athletes, coaches and wellness enthusiasts a deeper read on how their body responds to training, recovery and daily performance, turning metabolic data into decisions you can act on.*

*DMA® Performance is a sport, wellness and performance-support solution. It is not a medical device and is not intended for the diagnosis, prevention, monitoring, prediction, treatment or alleviation of any disease or medical condition.

DMA® diagnostic

DMA® Diagnostic gives specialist physicians deeper insight to support differential diagnosis, disease characterization, monitoring and treatment personalization.

*DMA® Diagnostics is currently under development. It is not yet certified and is not commercially available as an approved diagnostic medical device.

How DMA® Test works

The DMA® process is designed to provide real-time insights and data-driven guidance in a few simple steps:

1
Visit an HBI
Individuals visit a local HBI, such as a pharmacy, hospital, or medical center, for their assessment.
2
Customized protocol selection
A certified biologist or physician selects the specific protocol tailored to the individual’s needs, using a local DMA® station. The bio-sensors then collect real-time data and transmit it securely to the DMA® Cloud Computing Center.
3
Real-time AI-driven analysis
Advanced AI algorithms analyze the data in real-time, generating actionable insights that guide the healthcare provider during the visit. A detailed DMA® Report is automatically created, providing a comprehensive picture of the patient’s metabolic health.

Patent & Certifications

CE Certification for Electromagnetic Compatibility: completed.

DMA® meets the safety, health, and environmental protection requirements established by the regulations of the European Union (CE for Electromagnetic Compatibility) The CE (electromagnetic compatibility) certification obtained, with the support of the MISTER Consortium (CNR – National Research Council) and the test laboratory ELICA.

MDR Class I certification / ISO 13485: ongoing.

Class I devices are intended for non-diagnostic purposes, allowing the product to enter the market in the shortest possible time.
In parallel, the quality management system (QMS) will be updated to comply with ISO 13485, the international standard for medical device quality systems.
While ISO 13485 is not mandatory for Class I devices, aligning with it at this stage is essential to facilitate future certification upgrades.

MDR Class IIa certification: ongoing.

The second step will be to upgrade the device classification to MDR Class IIa.
This certification will expand the DMA’s intended use, allowing it to serve as a diagnostic support tool for physicians.
Achieving Class IIa status requires a more rigorous technical file and compliance with stricter regulatory requirements.

FDA Clearance: ongoing.

The final step will be obtaining FDA clearance for the Class IIa device.
This will enable commercialization of the DMA device in the United States, ensuring compliance with FDA’s regulatory standards for medical devices.